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Accupril (Quinapril)

Accupril is an angiotensin-converting enzyme (ACE) inhibitor and it is used to treat conditions like high blood pressure and manage heart failure.
Batch Expiry Date: November 2019
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Drug Uses

Accupril is used to treat or lower high blood pressure and manage heart failure and it works by involving certain chemical reactions that constrict (narrow) blood vessels and cause sodium and fluid retention by the kidney.


Medication must always be taken as advised by your medical practitioner/physician. If you are unsure, then please contact your physician for precise instructions. On the other hand, the medicine label usually contains dosage instructions which also may be followed.

You are advised to take Accupril at least 1 hour before or 2 hours after a meal or dairy product.

Maintain a gap of at least 2-3 hours with tetracyclines (eg, doxycycline) or fluoroquinolones (e.g., ciprofloxacin), take it at least 3 hours apart from Accupril. This product contains magnesium, which can interfere with absorption of these antibiotics.

Medications are prescribed according to a dosage schedule which must be completed in order to reap the benefits of the treatment. Lapsed schedules render Accupril ineffective. So, never stop in between unless advised by your physician.

One of the best ways to ensure that you do not miss out on a dose is to maintain a fixed regime for consuming Accupril each day.

Drug Class and Mechanism

Accupril falls under angiotensin-converting enzyme (ACE) inhibitor and it works by involving in certain chemical reactions that constrict (narrow) blood vessels and cause sodium and fluid retention by the kidney.

Missed Dose

You must maintain a schedule for taking the medicine at the same time each day so that you do not miss out on any doses. But, in the advent of a missed dose, take it as soon as you remember so that you can compensate for the loss of the dose.

But, then you may need to adjust your remaining doses accordingly. And if it is almost time for the next dose, then please skip the missed dose and continue with the normal schedule.

Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects.


Accupril must be stored at a cool and dark place that prevents it from direct exposure to sunlight. It should also be protected from kids and pets. You can store it at room temperature between 59 and 86 degrees F (15 and 30 degrees C.


If you are allergic to any ingredient in Accupril (you may check medicine label) then please do not use it without consulting your doctor.

You must also avoid using Accupril if

you are in the second or third trimester of pregnancy;
you have a history of angioedema (swelling of the face, lips, throat, or tongue) caused by treatment with an ACE inhibitor.

Ensure that your doctor is aware of your past and current medical history before you start any new treatment or medication. This must include any and all diseases that you have suffered /suffer from, all subscription and over the counter medication that you are taking, including vitamins and herbal supplements. This will help avoid a possible interaction or allergy.

Accupril is known to make some people dizzy or drowsy. And if you consume alcoholic beverages, then the chances of this happening increase greatly. Hence, alcohol and alcoholic beverages must be strictly avoided while taking Accupril. If you have experienced drowsiness after taking Accupril, then avoid tasks that require mental alertness for example, driving, handling heavy equipment or machinery etc.

Certain laboratory tests may be made mandatory while you are using Accupril. These tests include electrolyte levels and are conducted to analyze your progress to treatment and guage the degree to which side effects are being experienced. You must never miss out on any such lab tests.

Your lab technician or doctor must be informed that you are taking Accupril before you undergo any lab tests or emergency surgical procedures.

New patients who start using blood pressure medication often feel tired, worn out and lethargic during the first few weeks of starting treatment. If you are experiencing this, then do not stop treatment. Instead, contact your doctor but continue to use the medication.

Some blood pressure medications may alter the sodium levels in the body. The risk of this occurring increases severely in patients who have kidney problems, who are ill or who are aged.

So, ensure that you check the sodium content in medications or food items before you consume it.

Muscle weakness, slow or irregular heartbeat are some of the symptoms of high sodium levels.

Situations like heavy sweating due to heat or exercise, vomiting, diarrhea, or other causes of fluid loss can quickly lower your blood pressure to dangerously low levels. So regulate your fluid intake accordingly if you are undertaking any such activity or are suffering from diseases which cause fluid loss.

Accupril is not to be used during pregnancy. Accupril may increase the risk of being sunburn and it is not so effective with the patients having black complexion.

If you are planning to have a baby or are pregnant already then you must seek advice from your doctor before using Accupril. Discuss the effects and possible risks that Accupril usage may have on the unborn baby. It has shown to cause death to unborn fetus.

If you are breast feeding your child, then too seek medical advice before using Accupril. Some drugs may be excreted in the breast milk and may harm the baby.
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