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Trazodone (Trazodone)

Trazodone is a tetracyclic antidepressant and it is used to treat conditions like depression, anxiety disorder and its symptoms (e.g., sleeplessness, tension), chronic pain.
Batch Expiry Date: November 2019
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Trazodone 100 mg

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Drug Uses

Trazodone is used to treat depression, an anxiety disorder (e.g., sleeplessness, tension), chronic pain and it works by increasing the activity of one of the brain chemicals (serotonin), which helps elevate mood.


Medication must always be taken as advised by your medical practitioner/physician. If you are unsure, then please contact your physician for precise instructions. On the other hand, the medicine label usually contains dosage instructions which also may be followed.

Trazodone may be taken with a meal or a light snack. It may take several days to show its effect.

Medications are prescribed according to a dosage schedule which must be completed in order to reap the benefits of the treatment. Lapsed schedules render Trazodone ineffective. So, never stop in between unless advised by your physician.

One of the best ways to ensure that you do not miss out on a dose is to maintain a fixed regime for consuming Trazodone each day.

Drug Class and Mechanism

Trazodone falls under tetracyclic antidepressant and it works by increasing the activity of one of the brain chemicals (serotonin), which helps elevate mood.

Missed Dose

You must maintain a schedule for taking the medicine at the same time each day so that you do not miss out on any doses. But, in the advent of a missed dose, take it as soon as you remember so that you can compensate for the loss of the dose.

But, then you may need to adjust your remaining doses accordingly. And if it is almost time for the next dose, then please skip the missed dose and continue with the normal schedule.

Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects.


Trazodone must be stored at a cool and dark place that prevents it from direct exposure to sunlight. It should also be protected from kids and pets. You can store it at room temperature between 68 and 77 degrees F (20 and 25 degrees C).


If you are allergic to any ingredient in Trazodone (you may check medicine label) then please do not use it without consulting your doctor.

You must also avoid using Trazodone if you are allergic to any ingredient in Trazodone or nefazodone;
you are taking sodium oxybate (GHB).

Ensure that your doctor is aware of your past and current medical history before you start any new treatment or medication. This must include any and all diseases that you have suffered /suffer from, all subscription and over the counter medication that you are taking, including vitamins and herbal supplements. This will help avoid a possible interaction or allergy.

In some cases, the medication might be altered or require special attention like

if you are pregnant, planning to become pregnant, or are breast-feeding, if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement, if you have allergies to medicines, foods, or other substances, if you have heart disease including irregular heartbeat or have had a heart attack, if you have a history of depression or suicidal tendencies, if you are scheduled to have surgery, if you consume alcoholic beverages.

Certain medicines may interact with this drug like

Carbamazepine, ethanol, ginkgo biloba, HIV protease inhibitors (eg, ritonavir), phenothiazines (eg, thioridazine), or serotonin reuptake inhibitors (eg, fluoxetine).

Buspirone, carbamazepine, digoxin, hydantoins (eg, phenytoin), itraconazole, ketoconazole, nefazodone, serotonin reuptake inhibitors (eg, fluoxetine), or sodium oxybate (GHB).
Anticoagulants (eg, warfarin) because they may decrease Trazodone's effectiveness.

If you are planning to have a baby or are pregnant already then you must seek advice from your doctor before using Trazodone. Discuss the effects and possible risks that Trazodone usage may have on the unborn baby.

If you are breast feeding your child, then too seek medical advice before using Trazodone. Some drugs may be excreted in the breast milk and may harm the baby.
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